在COVID-19 mRNA疫苗相关心肌炎病例中医疗保健的利用率:一项匹配的回顾性队列研究
Zaeema Naveed1, Julia Li2, James Wilton3
1School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada; British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.
概括
疫苗相关心肌炎导致18个月的医疗保健利用率增加51%,大多数访问发生在接种疫苗后的前六个月. 这表明COVID-19疫苗接种者的预后是积极的.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 医疗保健服务研究 医疗服务研究
背景情况:
- COVID-19 mRNA 疫苗对于疫情控制至关重要.
- 肌心炎是一种与这些疫苗相关的罕见不良事件.
- 了解心肌炎后医疗保健利用情况对于患者管理和疫苗安全性评估至关重要.
研究的目的:
- 评估疫苗相关心肌炎患者与没有疫苗相关心肌炎患者的全因医疗利用率.
- 量化疫苗相关心肌炎在18个月内对医疗保健资源使用的影响.
主要方法:
- 在不列颠哥伦比亚省接受COVID-19 mRNA疫苗接种的12岁以上个人的回顾性队列研究.
- 接种后21天内被定义为心肌炎的暴露.
- 用于比较暴露和未暴露组之间的医疗保健利用率的差异差异分析.
主要成果:
- 在接种疫苗相关心肌炎的个体中,在18个月内观察到医疗保健利用率总体增加了51% (比率比率 = 1.51).
- 在心肌炎后的最初六个月内,医疗保健利用率激增了125% (率比=2.25),随后恢复到基线率.
- 在18个月内,每人额外9.1次医疗保健访问与疫苗相关的心肌炎有关.
结论:
- 医疗保健访问的最初增加,主要是门诊随访,表明一种可管理的情况.
- 回到基线率表明,对于患有疫苗相关心肌炎的人来说,预后是积极的.
- 这些发现支持COVID-19 mRNA疫苗的整体安全概况.
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