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Updated: Jun 8, 2025

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利古斯提利德通过在结肠组织中非共价激活TRPA1来改善功能性便秘

Kaixue Zhang1, Guoqing Luan1, Wenjuan Liu1

  • 1State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, 300353, PR China.

Journal of ethnopharmacology
|November 3, 2024
PubMed
概括

天 (AS) 通过激活TRPA1通道与ligustilide (Lig) 来治疗便秘,增加粘液分泌. 这项研究阐明了AS和Lig的机制,以缓解便秘.

关键词:
药品中的活性成分 药品中的活性成分安吉丽卡·西内尼斯 (Angelica sinensis) 是一个功能性便秘是一种功能性便秘.利古斯蒂化物这是粘液分泌的分泌物.这是TRPA1激动剂.

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