在接受体外膜氧化治疗的儿科患者中的鼻腔感染:系统性审查和元分析
1Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
The Journal of hospital infection
|November 3, 2024
概括
在外体膜氧化 (ECMO) 的儿科患者中,鼻腔感染很常见,呼吸道感染和葡萄球菌很常见. 然而,这些感染并没有显著增加该人口的死亡风险.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 传染病 传染病 传染病
- 身体之外的生命支持.
背景情况:
- 鼻腔感染是接受体外膜氧化 (ECMO) 的儿科患者的主要并发症.
- 了解这些感染至关重要,因为儿科患者经常从ECMO治疗中获得显著益处.
- 此前对这种特定人群的医院感染的分析是有限的.
研究的目的:
- 系统地审查儿科ECMO患者医院内感染的发病率,时间和来源.
- 识别主要病原体,抗生素使用模式和相关风险因素.
- 评估医院感染对该患者群体死亡率的影响.
主要方法:
- 在七个数据库中进行了系统的文献搜索.
- 使用 Stata 15.0 对综合效应和置信区间的元分析.
- 描述性分析用于其他收集的数据.
主要成果:
- 病床感染的总发病率为0.19 (95% CI:0.170.22).
- 呼吸道感染是最常见的,其中Staphylococcus物种是主要的病原体.
- 长时间的ECMO支持 (OR = 1.09) 增加了感染风险,但感染并没有显著增加死亡率 (OR = 1.44).
结论:
- 在儿科ECMO患者中,鼻腔感染很普遍,受到多种因素的影响.
- 呼吸道感染和葡萄球菌是常见的罪祸首.
- 尽管病房感染很常见,但在这个队列中,病房感染与死亡率的增加没有相关性.
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