左心室体积作为运动能力和功能独立的预测者,在正常射出小部分的个体中
Stephanie Rowe1,2,3, Wouter L'Hoyes4, Mauricio Milani4,5,6
1HEART Lab, St Vincent's Institute of Medical Research, Fitzroy, Australia.
European journal of preventive cardiology
|November 3, 2024
概括
小左心室 (LV) 尺寸预测心肺呼吸能力 (CRF) 低和功能障碍. 这种心声回声测量是不同人群中CRF最强的独立预测指标.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 低心肺呼吸能力 (CRF) 与不良健康结果有关,包括残疾,心力衰竭和死亡率.
- 左心室 (LV) 末端透析体积 (LVEDV) 与CRF有相关性,但其低CRF的诊断值仍未确定.
研究的目的:
- 评估LV终端透析体积 (LVEDV) 作为低心肺呼吸能力 (CRF) 的诊断标记物的实用性.
- 为了比较LVEDV的预测能力与其他回声心脏学测量来识别低CRF和功能障碍.
主要方法:
- 一项多中心国际队列研究,涉及2876名不同健康状况的个人.
- 心声图被用来测量LV大小,心肺运动测试评估了CRF (氧气吸收峰值[峰值VO2]).
- 分析了绝对和身体表面积指数的LVEDV (LVEDVi) 作为低CRF和功能障碍的预测指标.
主要成果:
- 在调整后,LVEDV显示出与峰值VO2 (R2=0.45) 最强的关联,并且仍然是最强的独立预测因子.
- 与大多数心声回声测量相比,LVEDV和LVEDVi在识别低CRF方面表现优越,并确定了最佳切断点.
- 较小的心室体积与较低CRF和功能独立值的更高概率有关.
结论:
- 休息LV大小是CRF和功能障碍的重要独立预测指标.
- 对LV大小的心声成像评估提供了一个有价值的工具,用于识别在健康和疾病的范围内的低CRF风险的个体.
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