口头训练可以通过增加白质完整性和灰质体积来改善神经认知和阅读表现
Ching-Chi Hsu1, Yun-Hsiang Wu2, Kang-Shuo Lee2
1Board of Directors, Wizcare Medical Corporation Aggregate, Taichung, Taiwan; International Intercollegiate Ph.D. Program, National Tsing Hua University, Hsinchu, Taiwan.
Experimental gerontology
|November 3, 2024
概括
关节训练改善了老年人的大脑结构. 这项为期4周的干预措施增强了灰色和白质,这表明在老年人群中潜在的认知功能增强.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 老年学是一门学科.
背景情况:
- 痴呆症和轻度认知障碍 (MCI) 给全球健康和经济带来了重大负担,预计到2050年将增加.
- 早期语言处理缺陷是阿尔茨海默病和MCI的特征.
- 关节训练有望改善痴呆症和MCI患者的沟通,符合传播缺陷假设.
研究的目的:
- 为了研究神经质变化在灰色和白质体积的响应口腔训练.
- 用voxel-wise分析来比较大脑结构的形态变化.
- 评估结构化的口语表达训练方案对老年健康成年人的认知功能的影响.
主要方法:
- 40名健康的日本老年人被随机分配到认知训练组或对照组.
- 该干预涉及为期4周的结构化口语表达训练方案,包括阅读任务.
- 使用神经成像技术 (3D解剖学,fMRI,扩散张力成像) 和行为评估.
主要成果:
- 关节训练导致左侧补充运动区域的灰质体积显著增加,中后环,双边上额头环.
- 观察到白质完整性的改善,在关键的语言相关区域增加了分数异性质.
- 在特定的大脑区域的阅读能力和皮质体积之间发现了相关性.
结论:
- 一个为期4周的口头表达训练计划显著增强了老年人灰质体积和白质完整性.
- 这些结构变化被观察到在大脑中对于语言处理至关重要的区域.
- 发音训练可以作为一种有价值的干预措施,以增强老年人群的认知和语言功能.
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