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在长期COVID后的运动后不适症诊断中进行为期两天的心肺运动测试

Chiara Gattoni¹, Asghar Abbasi¹, Carrie Ferguson¹

¹The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.

Respiratory physiology & neurobiology

|November 3, 2024

概括

长期COVID患者的运动后不适 (PEM) 是常见的,但在连续两天的测试中,运动能力并不不同. 这表明PEM不是由于运动能力恢复受损而引起的.

科学领域:

心肺血管生理学心肺血管生理学
后病毒综合征后病毒综合征
长期COVID研究研究

背景情况:

长期COVID的症状包括疲劳,运动不耐受和运动后不适 (PEM).
长期COVID中的PEM与肌痛性脑膜炎/慢性疲劳综合征 (ME/CFS) 的类似症状进行比较.
两天心肺运动测试 (CPET) 用于评估运动能力和潜在的PEM相关减轻.

研究的目的:

调查长期COVID患者对两天CPET协议的心肺和感知反应.
为了确定长期COVID中CPET连续两天的运动能力是否不同.
探索PEM和运动能力恢复之间的关系.

主要方法:

15名长期COVID患者接受了肺功能测试和两个CPET,隔24小时.
关键的CPET变量包括气体交换值,氧气吸收峰值和工作速度峰值.
使用修改后的DePaul症状问卷进行了评估.

主要成果:

80%的患者报告PEM.
所有参与者的肺功能都正常.
在第一天和第二天之间的CPET反应中没有发现显著差异.

结论:

在长期COVID患者中,PEM很普遍.
两天CPET反应没有差异表明PEM不是由于运动能力恢复受损.
需要进一步的研究来了解PEM在长期COVID中的机制.

关键词:

进行心肺运动测试.调整条件调整条件的调整运动耐受性运动耐受性疲劳疲劳疲劳疲劳疲劳长时间的COVID.这就是PEMEM的意义.

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