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Updated: Jun 8, 2025

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy
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在帕金森病模型中,GSK-3β抑制剂通过调节TFEB来放大自-溶酶途径

Jiahong Zhong1, Xihui Yu2, Yunming Zhong1

  • 1Department of Clinical Pharmacy, Meizhou People's Hospital (Huangtang Hospital), Meizhou 514031, China.

Experimental neurology
|November 3, 2024
PubMed
概括

抑制糖原合成酶激酶-3β (GSK-3β) 通过增强TFEB-自-溶解体通路,改善神经元功能和运动缺陷,延缓帕金森病的进展. 这为帕金森病提供了潜在的新疗法策略.

关键词:
自 - 溶酶体通路自 - 溶酶体通路这是一种GSK-3β抑制剂.MPP (((+) 的意思是帕金森病的疾病.美国联邦税务法 (TFEB)

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