一个连续的多重分配随机试验的研究协议,以减少手术前后的酒精使用
Xintong Ju1, Jake Solka1, Estevan Pena1
1Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Contemporary clinical trials
|November 3, 2024
概括
这项研究研究了适应性干预措施,包括虚拟健康辅导,以减少手术患者的高风险酒精使用. 其目标是改善术后恢复和长期健康结果.
科学领域:
- 医学研究 医学研究
- 手术患者护理手术患者护理
- 行为健康干预措施 行为健康干预
背景情况:
- 高风险的酒精消费在外科手术期间对外科康复构成重大风险.
- 选择性手术患者往往无法获得以酒精为中心的教育和治疗.
- 本研究方案解决了有效干预措施的必要性,以减轻术后酒精风险.
研究的目的:
- 评估短期,非药物,治疗方法的有效性,以减少手术前后的酒精使用.
- 为了比较术前虚拟健康辅导 (VHC) 与增强常规护理 (EUC) 在降低高风险酒精使用.
- 确定12个月内持续减少饮酒的最佳术后策略.
主要方法:
- 酒精查和手术前干预研究 (ASPIRE-2) 研究采用了顺序,多重分配,随机试验 (SMART) 设计.
- 包括440名选择性非癌症手术患者 (年龄21至75岁),报告高风险酒精使用.
- 适应性干预包括手术前的VHC或EUC,随后是根据患者反应量身定制的术后策略.
主要成果:
- 这项研究旨在确定适应性干预措施在减少术后酒精消费方面的有效性.
- 它旨在确定长期减少酒精使用的最成功的术后策略.
- 其次要目标包括确定干预有效性的调节因素和评估手术结果.
结论:
- 该ASPIRE-2研究引入了一种创新的适应性干预方法,用于术后降低酒精含量.
- 这项研究解决了管理与选择性手术相关的酒精使用风险的关键需求.
- 预计这些发现将为临床实践提供信息,并改善手术患者的治疗结果.
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