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Updated: Jun 11, 2026

Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS
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虚拟查用于早期识别强效和选择性基因素脱乙酶6系列抑制剂

Shawn J Stachel1, Deping Wang2, Anthony T Ginnetti1

  • 1Department of Medicinal Chemistry, Merck & Co., Inc., PO Box 4, West Point, PA 19486, USA.

Bioorganic & medicinal chemistry letters
|November 4, 2024
PubMed
概括

虚拟查发现了四种新的强效和选择性的基因素脱乙酶6 (HDAC6) 抑制剂. 这些新型化合物显示出进一步药物开发的前景,扩大了可用的化学选择.

关键词:
这就是ALS.在 HDAC6 中.基斯脱乙酶抑制剂 基斯脱乙酶抑制剂虚拟选是一个虚拟的选.

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