两性小分子抗微生物:从阴离子抗微生物 (CAMP) 到与机制相关的,结构多样化的抗微生物

Jiani Yuan1, Jiaxing Wang2, Xiaoxue Li3

  • 1Department of Neurology, Joint Research Institution of Altitude Health and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China; Department of Pulmonary and Critical Care Medicine, Targeted Tracer Research and Development Laboratory, Institute of Respiratory Health, Frontiers Science Center for Disease-related Molecular Network, Precision Medicine Key Laboratory of Sichuan Province & Precision Medicine Research Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.

概括

新型小分子抗微生物药物为打击抗生素耐药性的上升提供了有希望的解决方案. 这些化合物具有成本效益,稳定性和毒性较低,解决了当前治疗方法的关键局限性.

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