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内分泌干扰化学物质 - 从欧盟的角度看农药监管问题
Monika Liszewska1, Katarzyna Czaja1, Wojciech Korcz1
1Department of Toxicology and Health Risk Assessment, National Institute of Public Health NIH - National Research Institute, 24 Chocimska, 00-791 Warsaw, Poland.
Regulatory toxicology and pharmacology : RTP
|November 4, 2024
概括
植物保护产品中的内分泌干扰化学物质 (EDC) 在欧盟是一个令人担忧的问题. 本文回顾了当前的法规和欧盟委员会的活动,以限制来自PPP的EDC暴露.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 监管科学 监管科学
背景情况:
- 植物保护产品中的内分泌干扰化学物质 (EDC) 对欧盟社会构成风险.
- 欧盟条例 1107/2009要求对PPP活性物质,安全剂和协同剂的内分泌干扰 (ED) 特性进行调查.
研究的目的:
- 概述目前的欧盟方法,用于识别农药中的ED特性.
- 讨论影响PPP安全使用的监管问题.
- 分析欧盟委员会的努力,以减少来自PPP的EDC暴露.
主要方法:
- 审查欧盟法规 (例如, (EU) 2018/605, (EU) 2024/1487) 和指导方针 (ECHA/EFSA) 的情况.
- 对PPP成分批准的数据要求的分析.
- 审查交叉监管框架 (例如REACH,SCCS) 进行辅助剂危险评估.
主要成果:
- 为了评估PPP活性物质,安全剂和协同剂的ED特性,已有确定的科学标准和指南.
- 新的数据要求促进了对安全剂和协同剂的一致评估.
- 对配方剂危害的评估正在欧盟范围内进行讨论,考虑到更广泛的监管数据.
结论:
- 欧盟有一个框架来评估PPP中的ED特性,最近更新了安全剂和协同剂.
- 监管方法正在发展,通过整合来自其他框架的数据来解决配方剂危险.
- 欧盟委员会正在积极努力,以限制社会对PPP使用的EDC的暴露.
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