剖腹产后的利多卡因贴片:一个随机对照试验
Christopher K Arkfeld1, Anabel Starosta1, Ecem Esencan1
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT (Arkfeld, Starosta, Esencan, Athens, Lundsberg, Merriam).
American journal of obstetrics & gynecology MFM
|November 4, 2024
概括
局部利多卡因贴片在剖腹产后没有显著降低疼痛评分或阿片类药物使用. 需要进一步的研究,以有效的非阿片类药物疼痛管理在产后护理.
科学领域:
- 产科和妇科 产科和妇科
- 疼痛管理 疼痛管理
- 麻醉学 麻醉学
背景情况:
- 局部利多卡因贴片是一种常见的止痛药,但它们在剖腹产后疼痛管理中的有效性尚未得到充分证实.
- 研究新的止痛策略对于改善剖腹产后患者的治疗结果至关重要.
研究的目的:
- 评估添加局部利多卡因贴片在标准护理中对剖腹产后患者疼痛评分和阿片类药物消耗的影响.
- 评估产后期使用利多卡因贴片的安全性和患者满意度.
主要方法:
- 一项前性,随机化,对象盲控试验与100名接受剖腹产的患者进行.
- 参与者被随机分配,接受利多卡因贴片或安慰剂贴片.
- 主要结局包括视觉模拟尺度 (VAS) 疼痛评分和术后使用的总吗啡相当剂.
主要成果:
- 在术后1-4天,在利多卡因贴片和安慰剂组之间没有观察到平均最大或平均VAS疼痛得分的显著差异.
- 吸食阿片类药物 (吗啡等价物) 在两组之间也没有显著差异.
- 虽然在统计学上并不显著,但在利多卡因组中的63%的患者表达了未来使用的愿望,0%报告了护理中断.
结论:
- 在例行护理中添加局部利多卡因贴片并没有显著减少剖腹产后的疼痛或阿片类药物使用.
- 对产后期非阿片类药物疼痛管理选择进行进一步的研究是有必要的.
- 利多卡因贴片可能为一些患者提供安全的选择,但在本研究人群中没有显示出显著的止痛益处.
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