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在S4/S8处RPA2的O-GlcNAcylation对抗酸化,并在复制应激过程中调节检查点激活

Jianxin Zhao1, Guangcan Shao2, Xiaoxuan Lu1

  • 1Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing, China.

The Journal of biological chemistry
|November 4, 2024
PubMed
概括

与O结合的N-乙糖胺 (O-GlcNAc) 修改了复制蛋白A2 (RPA2),影响了DNA复制和应激反应. 这种O-GlcNAcylation对抗酸化,导致细胞循环缺陷.

关键词:
这就是O-GLcNAcc.在RPA2中使用RPA2.检查站检查站检查站检查站检查站酸化的方法是:光化.复制压力是复制的压力.

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