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Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
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作为治疗持久性病毒感染的方法之一的MitoTempo治疗?

Jasmin Mischke1, Sebastian Klein1, Markus Cornberg1

  • 1Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany; Twincore, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research (HZI) and the Hannover Medical School, Hannover, Germany; German Center for Infection Research (DZIF), Partner-site Hannover-Braunschweig, Hannover, Germany; Centre for Individualised Infection Medicine (CiiM), a joint venture between the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH), Hannover, Germany.

Virology
|November 4, 2024
PubMed
概括

针对线粒体的抗氧化剂MitoTempo显示,在慢性感染中,病毒载量暂时下降. 然而,它并没有显著地恢复老鼠模型中耗尽的T细胞功能.

关键词:
CD8 (((+) T细胞是T细胞中的一个.慢性病毒感染 慢性病毒感染免疫检查点抑制剂疗法免疫检查点抑制剂疗法淋巴细胞性胆膜炎病毒在我的时间,我的时间.特定于病毒的T细胞.

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