认知行为疗法与选择性血清素再吸收抑制剂结合用于早泄:系统性审查和元分析
Liang Li1, Hao Geng2, Meng Chen3
1Department of Urology, Fuyang People's Hospital, Fuyang, Anhui, China.
Andrology
|November 4, 2024
概括
认知行为疗法 (CBT) 与选择性血清素再吸收抑制剂 (SSRI) 结合,有效治疗早泄 (PE),改善性满意度而不增加副作用. 这种组合疗法为患有PE的男性提供了安全和可行的治疗选择.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 精神病学是一个精神病学.
- 性医学性医学性医学性医学
背景情况:
- 早泄 (PE) 是一个普遍存在的男性性障碍.
- 认知行为疗法 (CBT) 在PE治疗中已证明有效.
- 审查了CBT和SSRI对PE的联合疗效和安全性的证据.
研究的目的:
- 审查目前关于结合CBT与SSRI治疗PE治疗的有效性和安全性的证据.
- 综合来自随机对照试验 (RCT) 的研究结果,将组合治疗与单独的SSRI进行比较.
主要方法:
- 进行了RCT的系统审查和元分析.
- 在多个数据库 (CNKI,Wanfang,VIP,CBM,PubMed,Embase,Cochrane图书馆) 进行了搜索.
- 数据分析使用了STATA 17.1软件,使用Cochrane评估人员手册5.3.3评估文献质量.
主要成果:
- 包括15个高质量的RCT,涉及1243名患者.
- 与单独使用SSRI相比,组合疗法显著延长了阴道内射精潜伏时间 (IELT).
- 观察到患者和配偶的感知性射精控制,CIPE-5分数和性满意度有所改善,副作用没有显著差异.
结论:
- 与SSRI结合的CBT是一种可行的,有效的PE治疗方法.
- 认知和行为训练,或单独的行为训练,作为SSRI的附加剂,都是有效的.
- 组合疗法显示出良好的安全性,但并没有显著增加不良反应.
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