用于口腔手术的类固醇抗炎药物:系统性审查和元分析
Cristiana Palmela Pereira1,2,3, Madalena Mourão Tropa4,5, Rui Santos2,6
1FORENSEMED from UICOB, Faculty of Dental Medicine University of Lisbon, Portugal.
Acta stomatologica Croatica
|November 4, 2024
概括
非类固醇抗炎药物 (NSAIDs) 可以管理口腔手术后的疼痛. 中期NSAIDs,酸衍生品和酸衍生品显示出有效性,常见的处方是布洛芬400mg.
科学领域:
- 口腔手术和疼痛管理.
- 抗炎药物的药理学.
背景情况:
- 手术后的疼痛,胀和三风在口腔手术后很常见.
- 非类固醇抗炎药物 (NSAIDs) 经常被处方用于缓解疼痛.
研究的目的:
- 为了比较不同的药物治疗方案在口腔手术后缓解急性疼痛的有效性.
- 分析NSAIDs在口腔外科手术后对疼痛,胀和三症的影响.
主要方法:
- 在PubMed,Cochrane和Scopus中进行系统的文献搜索 (2013-2023年).
- 包括在口腔手术之前或之后对NSAID处方的临床试验.
- 关于疼痛,胀和三症结局的元分析和元回归结果.
主要成果:
- 包括36项研究 (30项前性研究),其中女性占主导地位.
- 中期NSAIDs,酸衍生物和酸衍生物显示减少疼痛和胀.
- 3天或更短时间内每8小时服用400毫克的布洛芬经常被处方.
结论:
- 手术后的疼痛,胀和三症可以通过NSAIDs来管理.
- 特定的NSAID类 (中期,酸,酸衍生物) 对于疼痛和胀是有效的.
- 证据质量低至非常低;发现需要谨慎解释.
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