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Updated: Jun 8, 2025

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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特拉贝克丁在骨肉瘤模型中促进瘤性病毒抗瘤疗效,病毒基因表达和免疫效应器功能

Emily M Ringwalt1,2, Mark A Currier1, Andrea M Glaspell1

  • 1Center for Childhood Cancer Research, Nationwide Children's Hospital, Columbus, OH 43215, USA.

Molecular therapy. Oncology
|November 4, 2024
PubMed
概括

特拉贝克丁通过破坏抗病毒反应和减少免疫抑制细胞来增强瘤性简单疹病毒免疫疗法. 这种组合疗法通过直接杀死病毒和增强细胞毒性淋巴细胞活性促进免疫介导的瘤回归.

关键词:
尤文肉瘤 (Ewing Sarcoma) 是一种癌症.癌症免疫疗法免疫疗法简单疹病毒 (HSV-1) 病毒免疫激活系统的激活骨质肉瘤是骨质肉瘤的一种疾病.协同效应是一种协同效应.在trabectedin中进行了追踪病毒免疫疗法病毒免疫疗法病毒疗法病毒疗法

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