致使骨科患者在第三级护理医院出现术后植入物感染的生物
Raja Muhammad Mussab1, Sharjeel Khan1, Saad Zulfiqar Bubak2
1Trauma and Orthopaedics, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Cureus
|November 4, 2024
概括
葡萄球菌和Klebsiella物种是最常见的骨科植入物感染的原因. 这突显出迫切需要审查抗生素预防策略,这是由于日益增加的グラム阴性细菌.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 手术部位感染 (SSI) 是骨科植入物程序的一个重要并发症.
- 这种疾病导致长时间住院,增加发病率,更高的再入院率,以及相当大的财务负担.
- 识别常见的致病生物对于有效的治疗和预防策略至关重要.
研究的目的:
- 确定导致术后植入物感染的主要微生物.
- 为优化骨科手术中的抗微生物预防和治疗方案提供数据.
主要方法:
- 一项涉及196名手术后植入物感染患者的三级护理医院的横截面研究.
- 从18-65岁的患者收集了人口统计和临床数据.
- 来自受感染的植入部位的抽样被培养用于微生物识别和抗生素敏感性测试.
主要成果:
- 克莱布塞拉 (26%) 和金黄色葡萄球菌 (25.5%) 是最常见的病原体.
- 其他确定的生物包括Pseudomonas物种 (16.3%),Acinetobacter物种 (13.8%),大肠杆菌 (11.7%) 和凝结酶负型葡萄球菌 (6.6%).
- 患者的平均年龄为48.47岁,性别分布几乎平等 (49%为女性,51%为男性).
结论:
- 葡萄球菌和Klebsiella物种是骨科植入物感染的主要原因.
- 克莱布西拉菌的日益流行表明,微生物耐药性模式的潜在变化.
- 目前的预防性抗生素策略需要重新评估,以应对日益增长的グラム阴性细菌感染的发病率.
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