欧洲口腔癌负担的发展趋势:系统性审查
Amr Sayed Ghanem1, Hafsa Aijaz Memon1, Attila Csaba Nagy1
1Department of Health Informatics, Institute of Health Sciences, Faculty of Health Sciences, University of Debrecen, Debrecen, Hungary.
Frontiers in oncology
|November 4, 2024
概括
口腔状细胞癌 (OSCC) 在欧洲越来越令人担忧,区域,性别和年龄差异显著影响发病率和存活率. 解决可修改的风险因素和改善早期检测对于更好的患者结果至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 口腔癌 (OCC),主要是口腔状细胞癌 (OSCC),是欧洲日益严重的健康问题,影响年轻人群.
- 可预防的生活方式选择和社会决定因素对整体疾病负担作出了重大贡献.
- 获得医疗保健的限制和诊断延迟加剧了治疗挑战,并降低了生存率.
研究的目的:
- 系统地审查和分析欧洲各地的OSCC流行病学,病因学,诊断,治疗和生存的当前趋势.
- 确定影响OSCC负担和结果的地理,人口和病因因素.
- 为OSCC预防和管理提供公共卫生策略的信息.
主要方法:
- 按照PRISMA指南进行了一次系统的文献审查.
- 在PubMed,GLOBOCAN和EUROCARE-5数据库中进行了全面的搜索.
- 收录标准集中在关于欧洲人群中OSCC的同行评审的英语文章上.
主要成果:
- 在欧洲各个地区观察到OSCC发病率,死亡率和预后的显著差异,其中东欧和中欧的负担最大.
- 与女性相比,男性的OSCC风险明显高于女性.
- 年龄差异影响了预期寿命和治疗结果,而人类乳头瘤病毒 (HPV) 是口腔癌的新兴风险因素.
结论:
- 关于欧洲OSCC负担和预后存在差异,受地区,性别和年龄的影响.
- 针对可修改的风险因素和加强早期检测是公共卫生方面的重要优先事项.
- 未来的研究应该优先考虑风险因素控制和个性化医疗,以改善患者的治疗结果,并减少欧洲的OSCC发病率.
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