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Updated: Jun 8, 2025

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德波提尼布在胆管癌中与MET放大:一个病例报告

Yen-Hao Chen^1,2,3,4, Yu-Ting Huang³, Fang-Ying Kuo⁵

¹Division of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, 833, Taiwan.

OncoTargets and therapy

|November 4, 2024

概括

胆管癌治疗通过向治疗取得了进展. 在一个患者中发现的MET放大导致了tepotinib的成功治疗,显示了部分反应和持续的益处.

科学领域:

肝胆道恶性瘤肝胆道恶性瘤
精确瘤学精确瘤学
分子诊断学分子诊断

背景情况:

胆管癌 (CCA) 是一种具有不良预后的侵袭性胆管癌.
对于不可手术的CCA,标准的第一线治疗包括gemcitabine加 cisplatin化疗.
对于在一线治疗中进展的患者而言,有效的选择有限.

关键词:

在MET中放大放大功率.没有NGS,没有NGS.胆瘤是一种胆瘤.德波提尼布 (tepotinib) 是一种药物.

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