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Updated: Jun 8, 2025

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
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Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay

Published on: June 9, 2017

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染色体乘客综合体 (CPC) 组件及其相关途径是有希望的候选人,可以区分常态敏感和放射性ATM突变细胞

Anne Dietz1, Prabal Subedi1, Omid Azimzadeh1

  • 1Section Radiation Biology, Federal Office for Radiation Protection/Bundesamt für Strahlenschutz, Oberschleißheim, Germany.

Biomarker insights
|November 4, 2024
PubMed
概括

蛋白质组分析显示,染色体乘客复合体中的蛋白质在健康细胞中受到辐射暴露后被下调,但不是在ATM缺乏细胞中,这表明它们在辐射敏感性预测中的作用.

关键词:
在AT基因突变的过程中,辐射敏感性 辐射敏感性染色体乘客综合体的旅行者基于质谱的蛋白质组学.

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