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一个横截面研究与动脉样硬化相关的因素

Guokui Dai¹, Xiangsheng Cai¹, Chuanjiang Ye²

¹Clinical Laboratory, Guangzhou Cadre and Talent Health Management Center, Guangzhou, China.

Frontiers in physiology

|November 4, 2024

概括

Carotid 动脉样硬化 (CAS) 在男性中更常见,并且与年龄和血压有关. 单细胞与高脂胆固醇比率 (MHR),甘油三糖-BMI (TyG-BMI) 和代谢得分 (METS-IR) 可以帮助预测CAS.

科学领域:

心血管医学心血管医学
公共卫生公共卫生
生物标志物生物标志物

背景情况:

动脉样硬化 (CAS) 是心血管和脑血管疾病的重要危险因素.
早期检测和风险分层对于疾病预防和管理至关重要.

研究的目的:

研究动脉样硬化 (CAS) 与各种临床和生化指标之间的关系.
确定CAS的新型预测标记,以帮助预防心血管和脑血管疾病.

主要方法:

对11028名接受健康检查的成年人进行了回顾性分析.
评估CAS患病率及其与人口,临床和炎症标志物的关联.
多变量逻辑回归和ROC曲线分析,以评估不同指数的预测性能.

主要成果:

动脉动脉硬化加厚 (CAT) 的CAS检测率为12.00%,动脉动脉硬化斑块 (CAP) 的检测率为25.11%.
男性的CAT和CAP率明显高于女性 (p < 0.001).
CAS独立地与男性性别,年龄增长和心血压升高,MHR,TyG-BMI和METS-IR有关.

结论:

CAS的患病率很高,特别是在男性中.
系统血压,禁食葡萄糖,MHR,TyG-BMI和METS-IR是CAS的独立风险因素,受年龄的影响.
性别,年龄和METS-IR的组合表明CAS的高预测价值.

关键词:

动脉动脉样硬化 - 动脉动脉样硬化跨截面研究是跨截面研究.影响因素影响因素.多变量逻辑回归分析.新的胰岛素抵抗指数

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