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风险因素和常规心脏起器植入器新发性心力衰竭的发生率:一项全国性的研究
Maiwand Farouq1,2, Cecilia Rorsman1,3, Sofia Marinko1,2
1Cardiology Section, Department of Clinical sciences, Lund University, Lund, Sweden.
Heart rhythm O2
|November 4, 2024
概括
心脏起器治疗增加了心力衰竭的风险,超过20%的患者在五年内发展出新发性心力衰竭 (HF). 经过验证的风险评分可以根据九个关键因素识别高风险个体.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 公共卫生 公共卫生
背景情况:
- 右心室节奏与新发性心力衰竭 (HF) 的更高风险有关.
- 了解心脏起器植入后HF的发生率,风险因素和长期影响至关重要.
研究的目的:
- 在植入心脏起器后的患者中调查新发性心力衰竭 (HF) 的发生率.
- 确定风险因素,并为新发性高频率开发预测得分.
- 评估新发性HF的长期预后影响.
主要方法:
- 在瑞典进行的一项全国性队列研究 (2005-2020年) 确定了接受心脏起器的患者,没有先前的HF.
- 与国家注册表的数据链接允许进行结果评估 (5年内新发性HF) 和风险因素识别.
- 一个风险评分被开发和验证使用识别的风险因素.
主要成果:
- 超过65,000名患者被纳入;21.0%的患者在植入后5年内发展出新发性HF.
- 新发性HF与5年死亡率增加有关 (41.2%与19.7%相比).
- 关键的危险因素包括年龄,男性性别,高血压,糖尿病,心房动,慢性肺/病,缺血性心脏病和心阻塞. 风险最高的四分之一为5.36的HF危险比率.
结论:
- 心脏起器治疗与5年内出现新发性HF的显著风险 (>20%) 相关.
- 确定了9个风险因素,构成了预测得分的基础.
- 开发的风险评分可以有效地识别患有新发性HF高风险的患者.
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