慢性低腰痛患者的吸烟和精神变化:一项比较研究
Guilherme Augusto Foizer1,2, Vagner Cleyton de Paiva3, Carlos Gorios4
1Universidade Estadual de Campinas, Campinas, SP, Brazil.
Acta ortopedica brasileira
|November 4, 2024
概括
吸烟显著增加了慢性腰部疼痛患者的MODIC变化的风险. 吸烟史和Modic变化的进展之间存在强烈的相关性,这表明了剂量-反应关系.
科学领域:
- 脊柱成像和退行性疾病
- 肌肉骨系统疾病的流行病学
- 烟草使用与健康
背景情况:
- 慢性腰部疼痛是一种普遍的疾病,通常与脊柱的退行性变化有关.
- 脊椎骨髓的一种退行性改变Modic变化,经常在患有腰部疼痛的患者中观察到.
- 生活方式因素 (如吸烟) 在莫迪克变化的发展和进展中的作用需要进一步调查.
研究的目的:
- 为了比较慢性腰部疼痛患者中吸烟者的患病率,有或没有Modic变化.
- 调查吸烟史和脊髓成像上Modic变化的进展之间的相关性.
主要方法:
- 进行了一项观察性病例控制研究,涉及68名患者 (340个脊椎段).
- 患者被分为有Modic变化和没有Modic变化的组.
- 统计分析包括奇平方测试的几率比率和斯皮尔曼的非参数测试与吸烟史 (包装年) 的相关性.
主要成果:
- 有Modic变化 (MG) 的组显示平均吸烟史为13.84包年.
- 在吸烟患者中观察到Modic变化的风险增加 (异常比率[OR]4.09).
- 在吸烟史 (包装年) 和Modic变化的严重程度 (Max-Modic和Sum-Modic分数) 之间发现了显著的相关性.
结论:
- 吸烟与慢性腰部疼痛患者发生Modic变化的风险明显增加有关.
- 吸烟程度和Modic变化的进展之间存在着显著的相关性.
- 这些发现强调了吸烟是脊柱Modic变化的潜在危险因素.
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