狗感染性呼吸道疾病综合体和与疾病相关的病原体的危险因素
Zenhwa Ouyang1, Daniel Joffe1, J Scott Weese1
1Department of Population Medicine (Ouyang, Bernardo, Poljak) and Department of Pathobiology (Weese), University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1; VCA Canada, Calgary, Alberta (Joffe); Merck Animal Health, Kirkland, Quebec (Porter); Vet et Nous Hopital Veterinaire St-Eustache Deux-Montagnes, Saint-Eustache, Quebec (Villemaire, Cardin); VCA Canada Island Animal Hospital, Nanaimo, British Columbia (Langelier); VCA Canada Blue Cross Animal Hospital, Sarnia, Ontario (Mcgill-Worsley); VCA Canada O'Sullivan Animal Hospital, Barrie, Ontario (Prost).
狗感染性呼吸道疾病综合体 (CIRDC) 经常与狗聚会有关. 狗类偏流感病毒 (CPIV) 和狗类呼吸道冠状病毒 (CRCoV) 是CIRDC病例中发现的关键病原体.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 狗的健康 狗的健康
背景情况:
- 狗感染性呼吸道疾病综合体 (CIRDC) 是狗中普遍存在的呼吸道疾病.
- 高密度的犬种群经常与CIRDC爆发有关.
研究的目的:
- 确定导致CIRDC的主要病原体.
- 确定与CIRDC诊断相关的风险因素,包括特定的病原体和环境暴露.
主要方法:
- 在加拿大进行了一项前性的多诊所病例控制研究.
- 在2017年4月至2018年5月期间,注册了110只狗 (74个病例,36个对照).
- 使用呼吸道PCR面板进行病原体检测.
主要成果:
- 狗类偏流感病毒 (CPIV),Bordetella bronchiseptica和狗呼吸道冠状病毒 (CRCoV) 在CIRDC病例中被确定.
- CPIV和CRCoV检测与CIRDC诊断显著相关 (OR:分别为14.42和8.64).
- 暴露于多个狗的聚会增加了CIRDC诊断的几率 (OR:3.39).
结论:
- CPIV,CRCoV和B. bronchiseptica是CIRDC的重要贡献者.
- 检测CPIV和CRCoV,以及接触狗聚会,在CIRDC疾病状况中发挥作用.
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