牙周病: 一种全身性疾病
German E M Villoria1,2, Ricardo G Fischer1, Eduardo M B Tinoco1
1Department of Periodontology, School of Dentistry, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Periodontology 2000
|November 4, 2024
概括
牙周炎,传统上被视为局部口腔疾病,越来越被认为是一种全身性疾病. 这种范式转变凸显了它对整体健康的影响及其与其他慢性非传染性疾病的联系.
科学领域:
- 牙周病学 牙周病学
- 系统健康 系统健康
- 慢性疾病流行病学 慢性疾病流行病学
背景情况:
- 牙周炎在历史上被认为是一种局部炎症状况,只影响口腔组织.
- 许多研究表明牙周炎与各种非传染性疾病 (NCD) 之间存在关联,包括心血管疾病,类风湿性关节炎和糖尿病.
- 然而,因果关系和牙周炎作为独立风险因素的作用仍然很难确定,因为许多研究的横截面性质和最近与多病症相关.
研究的目的:
- 提出一种模式转变,将牙周炎视为一种全身性疾病,而不仅仅是局部口腔疾病.
- 强调牙周炎会影响个体的整体系统状况和福祉.
- 倡导牙科和医疗专业将这种新视角纳入研究和临床实践.
主要方法:
- 这是一份意见书,综合了现有研究,并提出了一个新的概念框架.
- 它审查了牙周炎和其他全身性疾病之间的共同风险因素 (环境,生活方式,遗传) 和免疫病理.
- 它分析了与牙周炎相关的促炎,促血栓和免疫状态.
主要成果:
- 牙周炎与许多全身性疾病具有共同的风险因素和免疫病理.
- 系统性疾病可以产生一种促炎症状态,增加对其他慢性疾病的易感性,这种现象也在牙周炎中观察到.
- 牙周炎本身可以影响其他全身性疾病的易感性和进展,反之,并发病症可以影响牙周病.
结论:
- 牙周炎应该被认为是一种全身性疾病,对个人整体健康有重大影响.
- 这种观点将牙周病重新定义为慢性非传染性疾病的部分.
- 采用这种观点有助于理解牙周炎作为一种共同疾病,并认识到其他共同疾病如何影响其发病和进展.
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