沙门氏菌种类的毒性和抗菌耐药性模式. 从迁徙和被捕野生鸟类中恢复
Ruhena Begum1, Nilima Akther Asha1,2, Diponkar Chandra Chanda Dipu1
1Department of Medicine, Sylhet Agricultural University, Sylhet, Bangladesh.
Veterinary medicine and science
|November 4, 2024
概括
在野生鸟类中发现了沙门氏菌,特别是多抗药 (MDR) 和扩展谱β-乳糖酶 (ESBL) 菌株. 这些鸟类可以充当传播这些细菌的储.
科学领域:
- 兽医微生物学 兽医微生物学
- 公共卫生 公共卫生
- 动物传播疾病 动物传播疾病
背景情况:
- 沙门氏菌种类,特别是扩展谱β-乳糖酶 (ESBL) 耐药菌株,由于它们的流行和传播日益增加,构成了严重的全球健康威胁.
- 越来越多的野生鸟类,无论是迁徙的还是被囚禁的,都被认为是各种病原体的潜在储库.
研究的目的:
- 为了确定沙门氏菌种类的流行率. 在迁徙和养的野生鸟类中.
- 为了描述孤立的沙门氏菌菌株的抗微生物耐药性 (AMR) 和毒性基因配置文件.
主要方法:
- 从野生鸟类收集和分析了262个便样本.
- 标识沙门氏菌 spp. 的标识. 使用标准培养和PCR技术.
- 分子检测关键毒性和AMR基因,包括ESBL和sul1基因.
主要成果:
- 沙门氏菌的发病率为30.92%,在迁徙 (38.10%) 的鸟类中比在囚禁 (23.40%) 的鸟类中更高.
- 对四环素 (100%),安培 (58%) 和链杆菌素 (46%) 观察到高耐药率.
- 在74.07%的分离物中,多药性耐药性 (MDR) 普遍存在,ESBL基因 (blaTEM,blaSHV) 和sul1基因的显著检测.
结论:
- 沙门氏菌 spp. 沙门氏菌 在被捕和迁徙的野生鸟类中都存在.
- 这些鸟类作为潜在的储库,可以将多药耐药 (MDR) 和ESBL产生沙门氏菌菌株传播给其他动物和人类.
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