根据专家批准的要求,芬太尼的启动率
Oren Miron1,2, Yael Wolff-Sagy3, Mark Levin4
1Branch of Planning and Strategy, Clalit Health Services, Tel Aviv, Israel. Orenmir@post.bgu.ac.il.
Journal of general internal medicine
|November 4, 2024
概括
需要专家批准,可显著减少81%的非瘤性疼痛的芬太尼启动. 这一政策还降低了整体阿片类药物使用,证明了其在控制强效阿片类药物处方方面的有效性.
科学领域:
- 疼痛管理 疼痛管理
- 公共卫生政策 公共卫生政策
- 药物监督 药物监督 药物监督
背景情况:
- 不合理的芬太尼使用带来了成和过量服用的重大风险.
- 医疗保健系统寻求策略来减轻与强效阿片类止痛药相关的风险.
- 芬太尼是一种强大的合成阿片类药物,越来越多地用于治疗疼痛.
研究的目的:
- 评估强制性专家批准对启动非瘤性疼痛的芬太尼的影响.
- 评估政策实施后,整体阿片类药物处置的变化.
主要方法:
- 这是一项回顾性队列研究,利用克莱利特医疗服务 (Clalit Health Services) 的440万名成员的观察数据 (2021年7月至2023年7月).
- 在政策实施之前和之后 (2022年7月) 评估了芬太尼的启动率,并将其扩展为继续使用.
- 根据年龄进行了子组分析,并将阿片类药物的总开放量与预测率进行了比较.
主要成果:
- 在政策实施后,芬太尼的使用量下降了81% (人均每百万人口711到135).
- 在老年人群中,芬太尼开始使用的减少不那么明显.
- 与预测相比,阿片类药物总开放量 (MME) 在6个月下降了7%,在12个月下降了26%.
结论:
- 专家批准芬太尼的启动有效地减少了其在非瘤性疼痛中的使用,特别是在年轻患者中.
- 这一政策也导致了阿片类药物开放总量的逐渐减少.
- 强制性专家批准启动和继续使用芬太尼可能是控制强烈阿片类药物使用的宝贵工具.
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