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对复杂疾病中的基因组优先级的贝叶斯线性回归模型的评估

Tahereh Gholipourshahraki1, Zhonghao Bai1, Merina Shrestha1

  • 1Center for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.

PLoS genetics
|November 4, 2024
PubMed
概括

贝叶斯线性回归 (BLR) 模型有效地优先考虑复杂特征的基因组,优于MAGMA等现有方法. 多特征分析进一步提高了对2型糖尿病 (T2D) 等疾病的途径发现.

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