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Updated: Jun 8, 2025

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
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Published on: August 13, 2012

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蛋白激酶A的结构决定因素对于CFTR通道激活至关重要

Csaba Mihályi1,2,3, Iordan Iordanov1,2,3, Andras Szollosi1,2,3

  • 1Department of Biochemistry, Semmelweis University, Budapest H-1094, Hungary.

Proceedings of the National Academy of Sciences of the United States of America
|November 4, 2024
PubMed
概括

蛋白激酶A (PKA-C) 通过不同的结合和酸化部位激活囊性纤维化跨膜导电调节器 (CFTR) 通道. 膜绑定PKA-C对于CFTR激活至关重要,而细菌因素可能会干扰囊性纤维化患者的这一过程.

关键词:
这就是IPAJJ.通过N-米里斯托基化.这是一种PKI.这是一种cAMP依赖的蛋白质激酶.囊性纤维化症是什么

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