益生菌制剂对异常口臭的治疗疗效:一项追溯观察性研究
Ye Kan Li1, Fu Yuan Mou1, Xiao Xian Qian2,3
1Department of Stomatology, Minhang Hospital, Fudan University, Shanghai, People's Republic of China.
Journal of breath research
|November 4, 2024
概括
异常口臭,通常起源于小肠,与小肠细菌过度生长 (SIBO) 密切相关. 使用特定益生菌的治疗通过减少SIBO显著改善了口臭.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 异常口臭缺乏明确的原因和彻底的调查.
- 细肠细菌过度生长 (SIBO) 是一种潜在的,但尚未被探索的,在异常口臭症的因素.
- 额外口腔口臭通常会带来诊断上的挑战.
研究的目的:
- 为了调查SIBO在异常性口臭病原发生中的作用.
- 评估益生菌在治疗与SIBO相关的异常口臭时的疗效.
- 为了确定异常口臭是否主要是一种非口腔疾病.
主要方法:
- 对162名异常口臭患者和198名健康对照者的回顾性观察研究.
- 通过感官测试诊断口臭;通过乳糖呼吸测试确定SIBO.
- 治疗组接受了Bifidobacterium三重活力囊两个月.
主要成果:
- 在异常口臭患者 (74.69%) 和对照组 (3.03%) 中,SIBO阳性显著高于对照组 (3.03%).
- 益生菌治疗在80.17%的患者中消除了SIBO,在87.60%的患者中改善了口臭.
- 治疗后,SIBO阴性患者的口臭改善明显高于持久性SIBO病例.
结论:
- 异常口臭主要是一种口外疾病,通常来自小肠.
- SIBO是异常口臭的重要潜在原因之一.
- 益生菌治疗有效地解决了SIBO,并改善了异常口臭症状.
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