新生儿的振荡血压值:关于妊娠年龄的观察数据
Noah H Hillman1,2, Howard L Williams1, Rebecca Y Petersen1,2
1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Neonatology
|November 4, 2024
概括
早产婴儿的血压受出生时的妊娠年龄 (GA) 和纠正的妊娠年龄 (CGA) 的影响. 血压在生命的前两周迅速增加,然后随着时间的推移逐渐上升.
科学领域:
- 新生儿生理学 新生儿生理学
- 儿科心脏病学 儿科心脏病学
- 临床数据科学临床数据科学
背景情况:
- 现有的标准血压 (BP) 值对于早产婴儿受到小队列大小的限制.
- 电子医疗记录 (EMR) 为研究更大,更多样化的婴儿群体中BP趋势提供了宝贵的资源.
- 研究从早期妊娠年龄 (GA) 到40周纠正妊娠年龄 (CGA) 的血压进展对于了解婴儿心血管健康至关重要.
研究的目的:
- 为了确定从出生到40周修正妊娠年龄 (CGA) 的早产婴儿的规范血压百分位数.
- 分析出生时妊娠年龄和整个婴儿期血压轨迹之间的关系.
- 为了提供更新的,数据驱动的参考范围,用于缩血压 (SBP),腹缩血压 (DBP) 和早产婴儿的平均动脉压 (MAP).
主要方法:
- 一项回顾性队列研究利用了SSM卫生系统 (2013-2023) 中29323名婴儿 (140万个BP测量) 的数据.
- 婴儿出生时间>22 0/7至<41周GA,且有可用血压数据的婴儿也包括在内.
- 从EMR中提取了缩血压,腹缩血压和平均动脉压,并从出生到40周的CGA每周进行分析.
主要成果:
- 对于SBP,DBP和MAP的规范百分位数范围 (第1-99位) 产生了婴儿至40周CGA.
- 在所有妊娠年龄段,在生命的前两周观察到血压的快速增加.
- 在任何给定的CGA时的血压值在早期的GA出生时的婴儿中都更高,突出了出生GA对血压趋势的影响.
结论:
- 婴儿血压在很大程度上取决于出生时的妊娠年龄和测量时的修正妊娠年龄.
- 在出生后的前两周内,SBP,MAP和DBP的快速增加发生,随后会逐渐增加.
- 这些发现为监测早产婴儿心血管健康提供了重要的更新参考范围.
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