在接受或拒绝尼森基底复合的患者中喉回流
Adam Gardi1, Sriprachodaya Gaddam1, Philip Maxwell1
1Drexel University College of Medicine, Department of Otolaryngology - Head and Neck Surgery, Philadelphia, Pennsylvania.
Journal of voice : official journal of the Voice Foundation
|November 4, 2024
概括
laparoscopic或机器人尼森基层复合 (LNF) 与单独服用药物相比,显著改善了喉回流 (LPR) 控制. 接受LNF治疗的患者表现出更好的反流减少和症状改善.
科学领域:
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术创新 在外科创新.
背景情况:
- 喉回流 (LPR) 显著影响声音质量和喉症状.
- 外科干预,特别是尼森基底复合,被认为是耐火性LPR.
- 将手术结果与仅仅是医疗管理进行比较对于治疗决策至关重要.
研究的目的:
- 评估拉皮透视或机器人尼森基层复合 (LNF) 在改善语音结果和LPR症状方面的疗效.
- 为了比较LNF结果与LPR患者的抗逆流症医疗管理.
- 评估LNF对客观反流参数和临床症状得分的影响.
主要方法:
- 对被诊断患有LPR的患者和被认为是手术候选人的回顾性图表审查.
- 分类为两组:接受了尼森基底移植 (尼森-接受,n=50) 和拒绝手术 (尼森-拒绝,n=54).
- 治疗前和治疗后的反流检测得分 (RFS) 和24小时pH阻抗结果在组之间进行比较.
主要成果:
- 尼森接受的组在LNF后的多个近端和远端反流参数显著减少.
- 在接受尼森和拒绝尼森组之间观察到统计学上显著的反流减少差异.
- 接受尼森治疗的患者在RFS总得分和红斑亚类中显著改善,与接受尼森治疗的组相比,红斑和喉胀有显著差异.
结论:
- laparoscopic或机器人尼森基底复合提供优越的LPR控制与单独的医疗管理相比.
- LNF导致反流参数的客观改善和主观症状的减少.
- 对于对医疗治疗不耐药的LPR患者,应强烈考虑进行手术干预.
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