在阿基里斯肌病的大量注射:一个系统的审查
Rifat Hassan1, Daryl Poku1, Nafisa Miah2
1Faculty of Medicine, University of Southampton, University Road, Southampton, SO17 1BJ, United Kingdom.
British medical bulletin
|November 4, 2024
概括
高容量注射 (HVIs) 有效地减少阿基里斯肌病的疼痛并改善功能,特别是当包括皮质类固醇时. 这种安全的治疗方法提供了短期的好处,需要进一步的研究来确定长期的疗效.
科学领域:
- 整形外科 整形外科 整形外科
- 运动医学 运动医学
- 再生医学是一种再生医学.
背景情况:
- 阿基里斯肌病 (AT) 是一种普遍的疾病,特别是在跑步者中.
- 高容量注射 (HVIs) 被探索为AT的保守管理选项.
- 本系统性审查评估了HVI在AT治疗中的有效性.
研究的目的:
- 系统地审查已发表的关于高容量注射 (HVIs) 在治疗阿基里斯肌病 (AT) 的有效性研究.
主要方法:
- 系统审查遵循系统审查和元分析 (PRISMA) 准则的首选报告项目.
- 在 2023 年 9 月 13 日之前,对多个电子数据库 (PubMed,Embase,Cochrane,Web of Science,CINAHL,OVID) 进行全面搜索.
- 包括10项涉及460名参与者的研究,评估AT的HVI.
主要成果:
- 常含有盐水,局部麻醉剂和皮质类固醇的HVIs显示,足功能显著改善,疼痛减少.
- 与没有皮质类固醇的HVIs相比,用皮质类固醇补充的HVIs在疼痛和功能方面显示出更大的早期改善.
- 随着时间的推移,在HVI治疗中观察到阿基里斯肌厚度和新血管性的减少.
- 没有报告HVI的不良事件,即使使用皮质类固醇.
结论:
- 高容量注射 (HVIs) 是一种有效和安全的治疗方法,可以减少阿基里斯肌病的疼痛和不适,特别是在短期内.
- 皮质类固醇增强的HVIs在阿基里斯肌病的疼痛和功能方面提供了显著的短期益处.
- 需要进一步进行高质量的随机对照试验,并进行更长的随访期,以充分确定HVI对AT的长期疗效.
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