越南儿童流感严重的神经并发症
Sy Duc Nguyen1,2, Thi Huyen Trang Ngo3, Thi Viet Ha Nguyen1,2
1Department of Pediatrics, Hanoi Medical University, Hanoi, Vietnam.
Influenza and other respiratory viruses
|November 4, 2024
概括
严重的流感相关的神经并发症 (IANCs) 可以影响健康的儿童,导致显著的死亡率和后果. 疫苗接种对于预防儿童群体中这些严重结果至关重要.
科学领域:
- 儿科神经学 儿科神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 流感病毒通常会导致呼吸道感染.
- 神经学并发症 (IANCs) 是罕见但严重的,特别是在儿童中.
- IANCs可能是致命的,甚至可能发生在以前健康的儿童身上.
研究的目的:
- 描述患有严重流感相关的神经并发症的儿科患者的特征.
- 确定与儿童IANC相关的风险因素和结果.
主要方法:
- 在一个热带儿科中心进行了一项描述性研究.
- 评估了2022年10月至2024年2月期间被诊断患有严重IANC的儿科患者.
- 包括临床数据,实验室结果和神经成像发现.
主要成果:
- 在20名儿科患者中,80%的患者年龄在5岁以下,70%的患者以前没有任何健康问题.
- 所有患者都缺乏最近的流感疫苗接种;神经症状在发病后1天的中位数出现.
- 脑炎是最常见的并发症 (80%),肝酶和费里丁水平高;死亡率为20%,45%出现严重的后果.
结论:
- 流感相关的神经并发症严重,影响儿童的白质和灰质.
- 这些并发症可以发生在健康的儿童中,这强调了流感疫苗接种的重要性.
- 疫苗接种是儿童群体中针对严重IANC的关键预防策略.
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