2型糖尿病患者蛋白质摄入量和死亡率的模式:来自NHANESES的结果
Ahmad Jayedi1, Mahdieh-Sadat Zargar2, Ali Najafi3
1Social Determinants of Health Research Center, Semnan University of Medical Sciences, Bassij Blvd, P. O. Box 35147/99442, Semnan, Iran. ahmadjayedi@yahoo.com.
Scientific reports
|November 4, 2024
概括
健康的蛋白质摄入模式,富含植物性食品和鱼类,可能会降低2型糖尿病成年人的死亡风险. 相反,高红肉和蛋的饮食可能会增加这种风险.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 慢性疾病管理 慢性疾病管理
背景情况:
- 2型糖尿病是一个全球性的健康问题,与增加的死亡风险有关.
- 饮食模式显著影响2型糖尿病患者的健康结果.
- 了解蛋白质摄入模式对于管理与糖尿病有关的死亡率至关重要.
研究的目的:
- 调查饮食蛋白质摄入模式与2型糖尿病成年人全因死亡率之间的关联.
- 通过主要成分分析来识别不同的食蛋白质模式.
- 量化与不同蛋白质摄入模式相关的死亡风险.
主要方法:
- 从NHANES (1999-2018) 分析了4646名2型糖尿病成年人的情况.
- 估计来自11个动物和植物性食品组的蛋白质摄入量.
- 主要成分分析以确定饮食蛋白质模式.
- 考克斯比例危险回归模型用于评估死亡风险.
主要成果:
- 确定了四种蛋白质摄入模式:"健康"",红肉和蛋"",蔬菜/鱼类"和"乳制品/坚果".
- 对"健康"模式的更高坚持与23%降低所有原因死亡风险有关 (HR 0.77,95% CI:0.62,0.97).
- 较高的"红肉和蛋"模式的坚持与28%的全因死亡风险增加有关 (HR1.28,95% CI:1.06,1.54).
结论:
- 一种"健康"的饮食蛋白质模式,强调植物来源和鱼类,与2型糖尿病患者的死亡率降低有关.
- 丰富的"红肉和蛋"模式,低于鱼类和家禽,与死亡风险增加有关.
- 聚焦蛋白质来源的饮食修改可能是改善2型糖尿病生存的关键策略.
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