2008年至2019年期间在德国使用甲状腺诊断和治疗的趋势
Arulmani Thiyagarajan1, Niklas Koenen2,3, Till Ittermann4
1Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Scientific reports
|November 4, 2024
概括
德国甲状腺诊断和治疗趋势 (2008-2019) 显示甲状腺刺激激素 (TSH) 测量增加和使用levothyroxine. 这表明,尽管患病率下降,但甲状腺疾病的诊断和治疗可能过度.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 德国在1993年实施了一项国家缺乏预防计划.
- 项目后,甲状腺疾病的减少被观察到.
- 综合数据显示,最近甲状腺激素使用量有所增加.
研究的目的:
- 调查2008年至2019年德国甲状腺诊断和治疗的趋势.
- 分析甲状腺相关医疗保健利用率的特定年龄和年龄标准化流行情况.
- 识别潜在的过度使用诊断和过度治疗.
主要方法:
- 使用GePaRD数据库,覆盖约20%的德国人口.
- 确定甲状腺诊断的年度流行 (TSH测量,超声波,科学扫描,活检).
- 按性别分层的甲状腺治疗 (药物,手术,放射性治疗) 的评估年流行率.
主要成果:
- 年龄标准化TSH测量患病率在男性增加了44%,在女性增加了31%.
- 在男性和女性中,Levothyroxine的使用增加了约31%.
- 科学扫描和活检的使用率下降,而超声波显示没有明确的趋势. 胺胺使用,使用,甲状腺切除术和放射性治疗也减少了.
结论:
- 甲状腺疾病的患病率在2008年至2019年之间可能继续下降.
- 显著增加的TSH测量和levothyroxine使用表明潜在的过度使用和过度治疗.
- 对诊断和治疗模式进行进一步的调查是有必要的.
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