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在同类型的SARS-CoV-2主蛋白酶中的Allostery

Emanuele Fornasier1, Simone Fabbian1,2, Haidi Shehi1

  • 1Department of Chemical Sciences, University of Padova, via F. Marzolo 1, 35131, Padova, Italy.

Communications biology
|November 4, 2024
PubMed
概括

在SARS-CoV-2主要蛋白酶 (Mpro) 二次体使用一个全osteric 机制来调节病毒复制. 这种由基质结合驱动的动力性体控制着聚蛋白加工效率.

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