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Updated: Jun 8, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

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新型辅酶Q6遗传变异增加了对肺炎球菌疾病的易感性

Emma C Walker1,2, Sarah Javati3, Elizabeth M Todd1

  • 1Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA.

Nature immunology
|November 4, 2024
PubMed
概括

在COQ6的遗传变异增加儿童急性下呼吸道感染 (ALRI) 的易感性. 这项研究确定了一种特定的COQ6变异,与巴布亚新几内亚较高的ALRI发病率和死亡率有关.

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