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干细胞移植后骨髓质疏松性瘤中供体线粒体基因组变异的预后影响

Jing Dong1,2,3, Shahram Arsang-Jang4, Tao Zhang5

  • 1Division of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, HRC 5860, Milwaukee, WI, 53226, USA. jidong@mcw.edu.

Journal of hematology & oncology
|November 4, 2024
PubMed
概括

捐赠者线粒体DNA (mtDNA) 变异显著影响了接受异构造血细胞移植 (allo-HCT) 的骨髓质瘤 (MDS) 患者的结果. 结合这些变异可以完善预后模型和供体选择,以改善患者的生存率.

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