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氧化平衡得分与美国成年人代谢综合征特征之间的关联

Junxian Li^1,2, Ya Liu², Jingjing Li²

¹Department of Blood Transfusion, Key Laboratory of Cancer Prevention and Therapy in Tianjin, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.

Diabetology & metabolic syndrome

|November 4, 2024

概括

较高的氧化平衡评分 (OBS),反映了抗氧化剂和亲氧化剂的平衡摄入量,与降低代谢综合征 (MetS) 风险有关. 采用富含抗氧化剂的饮食和生活方式可能有助于预防代谢障碍.

科学领域:

营养科学营养科学
公共卫生公共卫生
生物化学生化学

背景情况:

代谢综合征 (MetS) 是一组疾病,增加患心脏病,中风和2型糖尿病的风险.
氧化应激,即亲氧化剂和抗氧化剂之间的不平衡,与MetS.的病变产生有关.
氧化平衡评分 (OBS) 基于饮食和生活方式因素来量化这种平衡.

研究的目的:

调查氧化平衡得分 (OBS) 与发展代谢综合征 (MetS) 的风险之间的关联.

主要方法:

一项横截面研究分析了NHANES数据库中的16850名参与者的数据.
使用20个亲和抗氧化因子计算了OBS.
使用加权后勤回归和限制立方线 (RCS) 来评估OBS-MetS关系.

主要成果:

在最高的OBS四分位数 (最低的氧化应激) 中的个体具有显著较低的MetS风险 (OR=0.55,95%CI:0.47-0.64).
较高的OBS与腹部肥胖,高血压,高甘油,低HDL-C和高空腹血糖 (FBG) 相反相关.
OBS与高血压/FBG之间的关联受BMI的影响;女性OBS较高的FBG风险显著降低.

结论:

较高的OBS,表明氧化应激因素的良好平衡,与降低MetS风险有关.
促进富含抗氧化剂的饮食和生活方式可能是预防代谢障碍的策略.

关键词:

饮食中的饮食饮食.禁食的血糖禁食的血糖生活方式生活方式代谢综合征是代谢综合征的一种.氧化平衡得分氧化平衡得分

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