注射的预测者在那些接受注射卡博特格拉维尔/里尔皮维林的人中观察了注射的坚持
Lucas Hill1, Jeffrey Yin1, Nimish Patel2
1University of California San Diego Owen Clinic, Sand Diego, CA; and.
Journal of acquired immune deficiency syndromes (1999)
|November 5, 2024
概括
错过长效注射药物 (LAI) 卡博特格拉维尔/里尔皮维林 (CAB/RPV) 检查的预测因素包括年轻的年龄和以前没有出现. 这些因素对于管理LAI CAB/RPV在艾滋病毒治疗中的坚持至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 艾滋病毒/艾滋病 治疗
- 药理学 药理学是指药理学的学科.
背景情况:
- 对于长效注射 (LAI) 卡博特格拉维尔/里尔皮维林 (CAB/RPV) 的注射访问的坚持预测因素的数据有限.
- 延迟注射对LAI CAB/RPV患者病毒抑制的影响需要进一步调查.
研究的目的:
- 在接受LAI CAB/RPV.的患者中确定错过注射访问的预测因素.
- 在这个人群中评估晚期注射和病毒抑制之间的关联.
主要方法:
- 一项回顾性队列研究分析了287名艾滋病毒成年患者在LAI CAB/RPV至少6个月 (2021年5月至2023年8月) 的数据.
- 数据包括人口统计数据,之前的办公室访问不显示,注射访问不显示和注射时间.
- 考克斯比例危险回归评估了错过或迟到注射的预测因素.
主要成果:
- 年龄较小和先前的办公室访问不显示预测错过的注射访问 (32.1%).
- 出生时分配的男性性别和年轻年龄与晚期注射 (15.3%) 有关.
- 晚期注射和可检测的病毒载量或病毒学失败之间没有发现显著的关系.
结论:
- 之前没有出现预测错过的LAI CAB/RPV注射访问.
- 年龄较小与错过和迟到的LAI CAB/RPV注射有关.
- 管理错过预约的策略对于在艾滋病毒护理中有效实施LAI CAB/RPV至关重要.
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