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在韩国报告的不良事件和相关因素 冠状病毒疾病 2019年疫苗接种
Hyunjin Park1,2, Eunsun Lim1,3, Seunghee Jun1,2
1COVID-19 Vaccine Safety Research Center, Seoul, Korea.
Journal of Korean medical science
|November 5, 2024
概括
接种COVID-19疫苗的不良反应 (AE) 在女性,年轻人以及具有较低社会经济地位或潜在健康状况的人群中更为常见. 持续监测对于疫苗安全和管理公共卫生问题至关重要.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 流行病学 流行病学
背景情况:
- COVID-19疫苗是有效的,但与不良事件 (AE) 有关.
- 持续监测对于疫苗安全和公共卫生管理至关重要.
- 了解副作用和风险因素可以为疫苗安全策略提供信息.
研究的目的:
- 描述COVID-19疫苗相关的不良事件 (AE).
- 为了确定与疫苗接种后的AE相关的风险因素.
- 调查疫苗剂量对AE的影响.
主要方法:
- 利用COVID-19疫苗接种记录,AE报告和医疗保健索赔 (2021年2月至2023年1月) 的链接数据库.
- 评估了疫苗接种后发生的副作用的频率和严重程度.
- 分析了与累积疫苗剂量和风险因素相关的副作用.
主要成果:
- 超过4200万人接种了疫苗;365,900人报告了副作用 (头痛,肌肉疼痛,发烧最常见).
- 女性,18至49岁的年龄段以及社会经济地位较低的个人中,AE报告的数量更高.
- 与健康个体相比,在患有潜在疾病 (例如COPD,喘) 的人群中观察到更高的AE报告风险.
结论:
- 女性,年轻人,社会经济地位较低的人,以及患有潜在健康状况的人报告了更多的副作用.
- 持续监测对于安全的疫苗接种实践至关重要.
- 在高风险群体中解决与疫苗有关的焦虑是很重要的.
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