检查点抑制剂治疗:与免疫相关的不良事件管理管理
Lori Davis1, Mary Beth Casselbury, Sharon Wilson
1Lori Davis and Mary Beth Casselbury are triage nurses, and Sharon Wilson is a clinical nurse leader at the Lipson Cancer Institute in Rochester, N.Y.
免疫检查点抑制剂可以在癌症治疗期间和之后引起与免疫相关的毒性 (irAEs). 患者教育计划有助于识别这些免疫疗法副作用和毒性.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 临床医学 临床医学
背景情况:
- 免疫检查点抑制剂 (ICI) 是现代癌症治疗的基石.
- ICI治疗经常与免疫相关的不良事件 (irAEs) 相关.
- 治疗期间或治疗后的任何时候都可能出现irAEs,这构成了临床挑战.
研究的目的:
- 讨论免疫检查点抑制剂治疗的前景.
- 描述患者教育计划的实施情况.
- 增强与免疫治疗相关的IRAE及其毒性的识别.
主要方法:
- 关于ICI治疗和irAEs的文献综述.
- 开发和实施患者教育计划.
- 专注于患者识别irAE症状和毒性.
主要成果:
- 与ICI相关的多个irAE的高患病率.
- 治疗期间和治疗后长达3个月可以发生irrAEs.
- 患者教育对于及时识别和管理至关重要.
结论:
- 免疫检查点抑制剂治疗需要对irAEs进行警监测.
- 患者教育计划对于提高对免疫疗法毒性的认识至关重要.
- 早期识别irAEs可能会改善患者的治疗结果.
更多相关视频
00:06An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
09:01Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
Published on: March 7, 2025
相关概念视频
Tumor Immunotherapy
Endocarditis IV: Nursing Management
Myocarditis III: Medical Management
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
Myocarditis IV: Nursing Management
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
