听力损失与抑郁风险的关联:系统性审查和元分析
Jingxuan Wei1, Yang Li2, Xiongbin Gui1,3
1Graduate School, Guangxi University of Chinese Medicine, Nanning, China.
Frontiers in neurology
|November 5, 2024
概括
听力损失与更高的抑郁风险有关. 这项对24项队列研究的元分析证实,听力损失是各种人口统计和研究设计中抑郁症的独立风险因素.
科学领域:
- 听力学和心理健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 以前的研究表明,听力损失和抑郁症风险之间存在联系.
- 在不同的随访期,年龄组和研究设计中,这种关联的确切强度尚不清楚.
研究的目的:
- 进行元分析以确定听力损失与抑郁症风险之间的关联.
- 调查跟踪时间,年龄和研究设计等因素如何影响这种关联.
主要方法:
- 在PubMed,Embase和Cochrane图书馆进行了全面的文献搜索.
- 来自24个队列研究 (2007-2024) 的数据,涉及超过25万名参与者,进行了综合和元分析.
- 研究质量使用纽卡斯尔-太华尺度进行评估,出版偏差使用漏斗图和埃格尔回归测试进行评估.
主要成果:
- 听力损失与抑郁症风险增加显著相关 (OR=1.35;95% CI:1.27-1.44).
- 在回顾性队列,老年人,突然神经感官听力损失 (SSNHL) 病例以及随访时间较长 (≥5年) 的研究中观察到更高的风险.
- 亚组分析显示,根据队列类型,年龄,听力损失的具体情况和随访时间,风险大小各不相同.
结论:
- 听力损失是抑郁症的一个独立风险因素.
- 这些发现强调了在心理健康评估和干预中考虑听力健康的重要性.
- 进一步的研究可能会探索连接听力损失和抑郁症状的潜在机制.
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