从兽医生物隔离和控制单元中分离出来的肠球菌的致病潜力
Catarina Geraldes1,2, Catarina Araújo1,2, Ana Catarina Pinheiro1,2
1CIISA - Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.
Frontiers in veterinary science
|November 5, 2024
概括
来自兽医单位的肠球菌株对常见抗生素具有很高的耐药性,并产生诸如血溶素和生物膜等毒性因子. 这凸显了预防医院获得感染 (HAI) 的警的必要性.
科学领域:
- 兽医微生物学 兽医微生物学
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 菌种类是医院获得感染 (HAI) 的重要贡献者.
- 在医疗保健机构中,对Enterococcus的耐药性和毒性概况的描述对于感染控制至关重要.
研究的目的:
- 来自兽医生物隔离和控制单元 (BICU) 的Enterococcus分离物的抗微生物耐药性和毒性因子的特征.
主要方法:
- 73从使用PCR的兽医BICU中鉴定出Enterococcus分离物.
- 选择了34个代表性分离物,并对抗微生物耐药性 (磁盘扩散) 和毒性因子表达 (血解素,生物膜) 进行了表征.
主要成果:
- 对红红素 (79.4%),安皮西林 (73.5%),阿莫西林 - 克拉夫兰酸 (70.6%),四环素 (67.6%),西普罗素 (58.8%) 和莱沃素 (50.0%) 的耐药性高.
- 大多数隔离物产生了血清素 (88.2%) 和生物膜 (82.3%).
- 8.8%的分离物被归类为高威胁,5.9%被归类为中等威胁的病原体.
结论:
- 在兽医环境中,Enterococcus菌株表现出显著的抗微生物耐药性和毒性.
- 在兽医单位和一般医疗保健设施中对这些菌株的持续监测对于预防HAI至关重要.
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