用于外门注射类固醇注射的化对比介质对甲状腺功能测试的影响
Ridvan Isik1, Serdar Kokar2, Yucel Olgun2
1Division of Pain Medicine, Department of Physical Medicine and Rehabilitation, Sakarya Training and Research Hospital, Sakarya, TUR.
Cureus
|November 5, 2024
概括
在 epidural 类固醇注射 (ESI) 中使用的化对比剂 (ICM) 显示了自由甲状腺素 (FT4) 水平的轻微增加. 在接受ICMESI手术的患者中,甲状腺功能没有受到影响.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 疼痛管理 疼痛管理
背景情况:
- 外周注射类固醇注射 (ESI) 通常使用含的对比介质 (ICM).
- ICM对甲状腺功能的潜在影响需要研究,特别是在ESI程序的背景下.
研究的目的:
- 检查ESI期间ICM暴露与甲状腺功能测试之间的关系.
- 评估ICM的ESI后甲状腺激素 (FT3,FT4,TSH) 的变化.
主要方法:
- 在大学医院疼痛管理中心进行前性观察性研究.
- 124名参与者 (18-65岁) 通过ICM获得了ESI.
- 甲状腺功能测试在ESI之前和ESI后三周进行.
主要成果:
- 在手术后观察到自由甲状腺素 (FT4) 水平的统计显著增加 (p = 0.017).
- 在自由三甲状腺激素 (FT3) 或甲状腺刺激激素 (TSH) 中没有发现显著变化.
- 在ICM的ESI后,没有参与者出现甲状腺疾病.
结论:
- 在ESI期间ICM的管理可能会导致FT4水平略有升高.
- 在接受ICM的ESI患者中,甲状腺功能在很大程度上保持稳定.
- 进一步的研究可能会探索这些FT4变化的临床意义.
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