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Updated: Jun 8, 2025

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选择适合特定再生需求的脱细胞化ECM的考虑因素

Shihan Zhang1, Yaru Guo1, Yixuan Lu1

  • 1Department of Geriatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, 100081, China.

Materials today. Bio
|November 5, 2024
PubMed
概括

脱细胞化细胞外基质 (dECM) 生物材料为组织修复提供了定制的环境. 这些多功能材料通过促进细胞生长和减少炎症以改善功能恢复来增强再生.

关键词:
脱细胞化细胞外矩阵生物材料物理化学特性 物理化学特性组织工程是组织工程.在dECM介导的再生过程的基本机制.

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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