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质量改善套餐可降低出生时体重非常低/极低的婴儿的低温症:系统性审查和元分析.
Guichao Zhong1, Jie Qi1, Lijuan Sheng1
1Department of Neonatology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, China.
PeerJ
|November 5, 2024
概括
质量改善包可以减少出生体重非常低 (VLBW) 和出生体重极低 (ELBW) 婴儿的低温症. 然而,这些干预措施可能会增加高温症的风险,特别是在VLBW婴儿中.
科学领域:
- 新生儿护理 新生儿护理
- 改善儿科的质量改善.
- 产周医学 产周医学
背景情况:
- 过早产生的婴儿的低温,特别是那些出生时体重非常低或极低的婴儿 (VLBW/ELBW),与增加的发病率和死亡率有关.
- 医疗机构越来越多地采用质量改善 (QI) 包,以减轻这一脆弱人群出生时的低温症.
- 这些QI包的有效性和安全性需要彻底评估.
研究的目的:
- 评估QI捆在减少VLBW/ELBW婴儿出生时低温的有效性.
- 评估QI捆的安全性,特别是检查高温症的发生率.
主要方法:
- 在PubMed,Embase,Cochrane图书馆和Web of Science进行了全面的文献搜索,截至2024年4月22日.
- 研究选择,数据提取和偏差风险评估是由两个研究人员独立执行的.
- 使用Review Manager 5.4.1进行了元分析,包括18项定性分析研究和12项定量元分析研究.
主要成果:
- 对于VLBW婴儿,QI捆绑显著减少轻度和中度低温 (或0.22,95% CI [0.13-0.37];或0.18,95% CI [0.15-0.22],分别),但增加了高温 (或2.79,95% CI [1.53-5.09]).
- 在ELBW婴儿中,QI捆绑降低了轻度和中度低温 (OR 0.46,95% CI [0.26-0.81];OR 0.21,95% CI [0.08-0.58],分别) 没有显著增加高温症 (OR 1.10,95% CI [0.22-5.43]).
结论:
- QI捆绑在减少VLBW和ELBW婴儿的低温症方面是有效的.
- 潜在的高温症增加,特别是在VLBW婴儿中,在实施QI捆绑时需要仔细监测和考虑.
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