2024年GCM和gcType:微生物菌株和基因组数据的全面资源
Guomei Fan1,2,3,4, Qinglan Sun1,2,3,4, Yan Sun1,2,3,4
1Microbial Resource and Big Data Center, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Nucleic acids research
|November 5, 2024
概括
世界微生物数据中心开发了全球微生物目录 (GCM) 和全球类型菌株目录 (gcType),以改善对微生物资源和数据的访问. 这些平台增强了微生物研究和分类学研究的数据共享.
科学领域:
- 微生物学 微生物学
- 生物信息学是一种生物信息学.
- 数据科学数据科学数据科学
背景情况:
- 微生物培养收集对于保存和分发微生物菌株和相关数据至关重要.
- 确保数据可查找性,可访问性,互操作性和可重复使用性 (FAIR) 对于最大限度地提高微生物资源的影响至关重要.
- 现有的数据平台需要改进,以有效地链接和挖掘来自不同微生物资源的信息.
研究的目的:
- 开发和实施微生物资源的综合平台,增强数据利用.
- 创建微生物菌株和类型菌株的综合目录,并提供详细的元数据.
- 促进数据挖掘,并将微生物信息与外部科学和专利文献联系起来.
主要方法:
- 世界微生物数据中心 (WDCM) 开发了全球微生物目录 (GCM) 和全球类型菌株目录 (gcType).
- 实现交互式接口,用于编目培养收藏场和注释类型菌株基因组.
- 集成精选的元数据 (生态系统,生长条件,位置) 和数据挖掘工具,链接到公共资源,文章和专利.
主要成果:
- 目前,GCM和gcType存储了来自51个国家的154个集合中的574,422个菌株,其中包括25980种类型的物种基因组.
- 整合了超过270万篇文章和103,000项专利,将微生物资源与科学文献和知识产权联系起来.
- 这些平台为探索微生物数据提供免费访问,交互式接口.
结论:
- GCM和gcType显著提高了微生物资源和培养集合的公平性和科学影响.
- 这些综合平台支持微生物分类学研究,并为"关于微生物资源和数字序列信息 (DSI) 的名古屋议定书"提供证据.
- 开发的系统为全球科学界提供了有价值的,可访问的资源.
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